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Microarray background correction: maximum likelihood estimation for the normal–exponential convolution

Background correction is an important preprocessing step for microarray data that attempts to adjust the data for the ambient intensity surrounding each feature. The “normexp” method models the observed pixel intensities as the sum of 2 random variables, one normally distributed and the other expone...

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Detaylı Bibliyografya
Asıl Yazarlar: Silver, Jeremy D., Ritchie, Matthew E., Smyth, Gordon K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648902/
https://ncbi.nlm.nih.gov/pubmed/19068485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxn042
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