A Systems Approach to Mapping DNA Damage Response Pathways

Failure of cells to respond to DNA damage is a primary event associated with mutagenesis and environmental toxicity. To map the transcriptional network controlling the damage response, we measured genomewide binding locations for 30 damage-related transcription factors (TFs) after exposure of yeast...

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Bibliographic Details
Main Authors: Workman, Christopher T., Mak, H. Craig, McCuine, Scott, Tagne, Jean-Bosco, Agarwal, Maya, Ozier, Owen, Begley, Thomas J., Samson, Leona D., Ideker, Trey
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811083/
https://ncbi.nlm.nih.gov/pubmed/16709784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1122088
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