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Validation and refinement of gene-regulatory pathways on a network of physical interactions

As genome-scale measurements lead to increasingly complex models of gene regulation, systematic approaches are needed to validate and refine these models. Towards this goal, we describe an automated procedure for prioritizing genetic perturbations in order to discriminate optimally between alternati...

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Detalhes bibliográficos
Main Authors: Yeang, Chen-Hsiang, Mak, H Craig, McCuine, Scott, Workman, Christopher, Jaakkola, Tommi, Ideker, Trey
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175993/
https://ncbi.nlm.nih.gov/pubmed/15998451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2005-6-7-r62
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