The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis

The repair of DNA double-strand breaks (DSBs) is essential to maintain genomic integrity. In higher eukaryotes, DNA DSBs are predominantly repaired by non-homologous end joining (NHEJ), but DNA ends can also be joined by an alternative error-prone mechanism termed microhomology-mediated end joining...

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Библиографические подробности
Главные авторы: Taylor, Elaine M., Cecillon, Sophie M., Bonis, Antonio, Chapman, J. Ross, Povirk, Lawrence F., Lindsay, Howard D.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2010
Предметы:
Genome Integrity, Repair and Replication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811014/
https://ncbi.nlm.nih.gov/pubmed/19892829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp905
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