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A NOVEL MECHANISM OF NUCLEOTIDE MISINCORPORATION DURING TRANSCRIPTION DUE TO TEMPLATE STRAND MISALIGNMENT
Transcription errors by T7 RNA polymerase (RNAP) may occur as the result of a novel mechanism in which the template base two positions downstream from the 3’ end of the RNA (TSn+1 base) is utilized during two consecutive nucleotide addition cycles. In the first cycle, misalignment of the template st...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810628/ https://ncbi.nlm.nih.gov/pubmed/17052458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.08.014 |
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