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Sonic hedgehog maintains proliferation in secondary heart field progenitors and is required for normal arterial pole formation

The Sonic hedgehog (Shh)-null mouse was initially described as a phenotypic mimic of Tetralogy of Fallot with pulmonary atresia (Washington-Smoak et al, 2005); however, subsequent reports describe only a single outflow tract, leaving the phenotype and its developmental mechanism unclear. We hypothes...

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Detalhes bibliográficos
Main Authors: Dyer, Laura A., Kirby, Margaret L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810612/
https://ncbi.nlm.nih.gov/pubmed/19361493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.03.028
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