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Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity

Sonic hedgehog (Shh) is an indispensable, extrinsic cue that regulates progenitor and stem cell behavior in the developing and adult mammalian central nervous system. Here, we investigate the link between the Shh signaling pathway and Hes1, a classical Notch target. We show that Shh-driven stabiliza...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wall, Dana S., Mears, Alan J., McNeill, Brian, Mazerolle, Chantal, Thurig, Sherry, Wang, Yaping, Kageyama, Ryoichiro, Wallace, Valerie A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615087/
https://ncbi.nlm.nih.gov/pubmed/19124651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805155
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