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Investigation of the Relative Cellular Permeability of DNA-binding Pyrrole-Imidazole Polyamides
Pyrrole-imidazole (Py-Im) polyamides are a group of chemicals that are able to bind specifically to DNA sequences in vitro and in mammalian cells. Using a cell based reporter assay, we investigated the size and linker affects on the cellular permeability of polyamides. We found that the conventional...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810552/ https://ncbi.nlm.nih.gov/pubmed/19610652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9002999 |
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