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Nuclear Factor κB Activation Contributes to Vascular Endothelial Dysfunction via Oxidative Stress in Overweight/Obese Middle-Aged and Older Humans

BACKGROUND: We tested the hypothesis that nuclear factor κB (NFκB) activity contributes to vascular endothelial dysfunction with aging and obesity in humans. METHODS AND RESULTS: We conducted a randomized, double blind, placebo controlled, crossover study in 14 non-diabetic overweight or obese (body...

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Detalhes bibliográficos
Main Authors: Pierce, Gary L., Lesniewski, Lisa A., Lawson, Brooke R., Beske, Stacy D., Seals, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810548/
https://ncbi.nlm.nih.gov/pubmed/19237660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.804294
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