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Longitudinal Association of PCSK9 Sequence Variations with LDL-Cholesterol Levels: The Coronary Artery Risk Development in Young Adults (CARDIA) Study
BACKGROUND: Mutations of PCSK9 are associated cross-sectionally with plasma LDL cholesterol (LDL-C) levels, but, little is known about their longitudinal association with LDL-C levels from young adulthood to middle age. METHODS AND RESULTS: We investigated the associations of 6 PCSK9 variants with L...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810147/ https://ncbi.nlm.nih.gov/pubmed/20031607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.108.828467 |
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