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Enhancing mTOR-targeted cancer therapy

BACKGROUND: The mammalian target of rapamycin (mTOR) has emerged as an attractive cancer therapeutic target. Accordingly, several mTOR inhibitors (e.g., rapamycin and its analogs; rapalogs) are currently being tested in many cancer clinical trials. Despite the encouraging results that some rapalogs...

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Detalhes bibliográficos
Main Authors: Wang, Xuerong, Sun, Shi-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810099/
https://ncbi.nlm.nih.gov/pubmed/19694499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728220903225008
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