Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice

Effective osteoporosis therapy requires agents that increase the amount and/or quality of bone. Any modification of osteoclast-mediated bone resorption by disease or drug treatment, however, elicits a parallel change in osteoblast-mediated bone formation because the processes are tightly coupled. An...

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Main Authors: Walker, Emma C., McGregor, Narelle E., Poulton, Ingrid J., Solano, Melissa, Pompolo, Sueli, Fernandes, Tania J., Constable, Matthew J., Nicholson, Geoff C., Zhang, Jian-Guo, Nicola, Nicos A., Gillespie, Matthew T., Martin, T. John, Sims, Natalie A.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2010
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810087/
https://ncbi.nlm.nih.gov/pubmed/20051625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40568
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