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Differential Effect of Saturated and Unsaturated Free Fatty Acids on the Generation of Monocyte Adhesion and Chemotactic Factors by Adipocytes: Dissociation of Adipocyte Hypertrophy From Inflammation

OBJECTIVE: Obesity is associated with monocyte-macrophage accumulation in adipose tissue. Previously, we showed that glucose-stimulated production by adipocytes of serum amyloid A (SAA), monocyte chemoattractant protein (MCP)-1, and hyaluronan (HA) facilitated monocyte accumulation. The current obje...

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Главные авторы: Yeop Han, Chang, Kargi, Atil Y., Omer, Mohamed, Chan, Christina K., Wabitsch, Martin, O'Brien, Kevin D., Wight, Thomas N., Chait, Alan
Формат: Artigo
Язык:Inglês
Опубликовано: American Diabetes Association 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809975/
https://ncbi.nlm.nih.gov/pubmed/19934003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0925
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