Engineered Zinc Finger Protein–Mediated VEGF-A Activation Restores Deficient VEGF-A in Sensory Neurons in Experimental Diabetes

OBJECTIVE: The objectives of the study were to evaluate retrograde axonal transport of vascular endothelial growth factor A (VEGF-A) protein to sensory neurons after intramuscular administration of an engineered zinc finger protein activator of endogenous VEGF-A (VZ+434) in an experimental model of...

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Autores principales: Pawson, Elizabeth J., Duran-Jimenez, Beatriz, Surosky, Richard, Brooke, Heather E., Spratt, S. Kaye, Tomlinson, David R., Gardiner, Natalie J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809974/
https://ncbi.nlm.nih.gov/pubmed/19934008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1526
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