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Transgenic Mice Expressing the Tyr437His Mutant of Human Myocilin Protein Develop Glaucoma

PURPOSE: To developed a genetic mouse model of primary open-angle glaucoma induced by expression of mutated human myocilin in transgenic mice and to test whether expression of mutated human myocilin in the eye angle structures produces more significant damage to the eye than does mutated mouse myoci...

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Bibliografske podrobnosti
Main Authors: Zhou, Yu, Grinchuk, Oleg, Tomarev, Stanislav I.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809368/
https://ncbi.nlm.nih.gov/pubmed/18436825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-1339
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