Constitutive WNT/Beta-Catenin Signaling in Murine Sertoli Cells Disrupts Their Differentiation and Ability to Support Spermatogenesis

Sertoli and germ cell interactions are essential for spermatogenesis and, thus, male fertility. Sertoli cells provide a specialized microenvironment for spermatogonial stem cells to divide, allowing both self-renewal and spermatogenesis. In the present study, we used mice with a conditional activate...

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Bibliographische Detailangaben
Hauptverfasser: Tanwar, Pradeep S., Kaneko-Tarui, Tomoko, Zhang, LiHua, Rani, Poonam, Taketo, Makoto M., Teixeira, Jose
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for the Study of Reproduction, Inc. 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809230/
https://ncbi.nlm.nih.gov/pubmed/19794154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.079335
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