Targeted disruption of mouse long-chain acyl-CoA dehydrogenase gene reveals crucial roles for fatty acid oxidation

Abnormalities of fatty acid metabolism are recognized to play a significant role in human disease, but the mechanisms remain poorly understood. Long-chain acyl-CoA dehydrogenase (LCAD) catalyzes the initial step in mitochondrial fatty acid oxidation (FAO). We produced a mouse model of LCAD deficienc...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Kurtz, David M., Rinaldo, Piero, Rhead, William J., Tian, Liqun, Millington, David S., Vockley, Jerry, Hamm, Doug A., Brix, Amy E., Lindsey, J. Russell, Pinkert, Carl A., O’Brien, William E., Wood, Philip A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1998
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28088/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9861014/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.26.15592
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