Targeted disruption of mouse long-chain acyl-CoA dehydrogenase gene reveals crucial roles for fatty acid oxidation

Abnormalities of fatty acid metabolism are recognized to play a significant role in human disease, but the mechanisms remain poorly understood. Long-chain acyl-CoA dehydrogenase (LCAD) catalyzes the initial step in mitochondrial fatty acid oxidation (FAO). We produced a mouse model of LCAD deficienc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kurtz, David M., Rinaldo, Piero, Rhead, William J., Tian, Liqun, Millington, David S., Vockley, Jerry, Hamm, Doug A., Brix, Amy E., Lindsey, J. Russell, Pinkert, Carl A., O’Brien, William E., Wood, Philip A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 1998
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC28088/
https://ncbi.nlm.nih.gov/pubmed/9861014
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg