Characterization of pertussis toxin analogs containing mutations in B-oligomer subunits.

The S2, S3, and S4 subunit genes of pertussis toxin (PT) from Bordetella pertussis were subjected to site-directed mutagenesis, and the resultant PT analogs were assayed for altered biological properties. PT analogs S2(T91,R92,N93) delta and S2(Y102A,Y103A) exhibited reduced binding to fetuin. Sever...

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Detaylı Bibliyografya
Asıl Yazarlar: Loosmore, S, Zealey, G, Cockle, S, Boux, H, Chong, P, Yacoob, R, Klein, M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1993
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC280851/
https://ncbi.nlm.nih.gov/pubmed/8500874
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