Characterization of pertussis toxin analogs containing mutations in B-oligomer subunits.

The S2, S3, and S4 subunit genes of pertussis toxin (PT) from Bordetella pertussis were subjected to site-directed mutagenesis, and the resultant PT analogs were assayed for altered biological properties. PT analogs S2(T91,R92,N93) delta and S2(Y102A,Y103A) exhibited reduced binding to fetuin. Sever...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Loosmore, S, Zealey, G, Cockle, S, Boux, H, Chong, P, Yacoob, R, Klein, M
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1993
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280851/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8500874/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.6.2316-2324.1993
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