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The Lever Arm Effects a Mechanical Asymmetry of the Myosin-V-Actin Bond
Myosin-V is a two-headed molecular motor taking multiple ATP-dependent steps toward the plus end (forward) of actin filaments. At high mechanical loads, the motor processively steps toward the minus end (backward) even in the absence of ATP, whereas analogous forward steps cannot be induced. The det...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808492/ https://ncbi.nlm.nih.gov/pubmed/20338849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.10.017 |
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