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Na(+) and K(+) Allosterically Regulate Cooperative DNA Binding by the Human Progesterone Receptor

Cooperativity is a common mechanism used by transcription factors to generate highly responsive yet stable gene regulation. For the two isoforms of human progesterone receptor (PR-A and PR-B), differences in cooperative DNA binding energetics may account for their differing transcriptional activatio...

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Autors principals: Connaghan, Keith D, Heneghan, Aaron F, Miura, Michael T, Bain, David L
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808462/
https://ncbi.nlm.nih.gov/pubmed/20000807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901525m
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