Virus-specific CD8(+) T cell numbers are maintained during γ-herpesvirus reactivation in CD4-deficient mice

The murine γ-herpesvirus 68 replicates in epithelial sites after intranasal challenge, then persists in various cell types, including B lymphocytes. Mice that lack CD4(+) T cells (I-A(b−/−)) control the acute infection, but suffer an ultimately lethal recrudescence of lytic viral replication in the...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Stevenson, Philip G., Belz, Gabrielle T., Altman, John D., Doherty, Peter C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1998
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28083/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9861009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.26.15565
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