Virus-specific CD8(+) T cell numbers are maintained during γ-herpesvirus reactivation in CD4-deficient mice
The murine γ-herpesvirus 68 replicates in epithelial sites after intranasal challenge, then persists in various cell types, including B lymphocytes. Mice that lack CD4(+) T cells (I-A(b−/−)) control the acute infection, but suffer an ultimately lethal recrudescence of lytic viral replication in the...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1998
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28083/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9861009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.26.15565 |
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