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Virus-specific CD8(+) T cell numbers are maintained during γ-herpesvirus reactivation in CD4-deficient mice

The murine γ-herpesvirus 68 replicates in epithelial sites after intranasal challenge, then persists in various cell types, including B lymphocytes. Mice that lack CD4(+) T cells (I-A(b−/−)) control the acute infection, but suffer an ultimately lethal recrudescence of lytic viral replication in the...

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Autors principals: Stevenson, Philip G., Belz, Gabrielle T., Altman, John D., Doherty, Peter C.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC28083/
https://ncbi.nlm.nih.gov/pubmed/9861009
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