Mast Cell-Derived TNF Can Exacerbate Mortality during Severe Bacterial Infections in C57BL/6-Kit(W-sh/W-sh) Mice

We used mast cell-engrafted genetically mast cell-deficient C57BL/6-Kit(W-sh/W-sh) mice to investigate the roles of mast cells and mast cell-derived tumor necrosis factor in two models of severe bacterial infection. In these mice, we confirmed findings derived from studies of mast cell-deficient WBB...

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Hlavní autoři: Piliponsky, Adrian M., Chen, Ching-Cheng, Grimbaldeston, Michele A., Burns-Guydish, Stacy M., Hardy, Jonathan, Kalesnikoff, Janet, Contag, Christopher H., Tsai, Mindy, Galli, Stephen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2010
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808097/
https://ncbi.nlm.nih.gov/pubmed/20035049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090342
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