Inhibition of Glycogen Synthase Kinase 3β (GSK3β) Decreases Inflammatory Responses in Brain Endothelial Cells

Immune mediators and leukocyte engagement of brain microvascular endothelial cells (BMVECs) contribute to blood–brain barrier impairment during neuroinflammation. Glycogen synthase kinase 3β (GSK3β) was recently identified as a potent regulator of immune responses in in vitro systems and animal mode...

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Hlavní autoři: Ramirez, Servio H., Fan, Shongshan, Zhang, Ming, Papugani, Anil, Reichenbach, Nancy, Dykstra, Holly, Mercer, Aaron J., Tuma, Ronald F., Persidsky, Yuri
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2010
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808093/
https://ncbi.nlm.nih.gov/pubmed/20056834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090671
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