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Inhibition of Glycogen Synthase Kinase 3β (GSK3β) Decreases Inflammatory Responses in Brain Endothelial Cells

Immune mediators and leukocyte engagement of brain microvascular endothelial cells (BMVECs) contribute to blood–brain barrier impairment during neuroinflammation. Glycogen synthase kinase 3β (GSK3β) was recently identified as a potent regulator of immune responses in in vitro systems and animal mode...

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Bibliografiske detaljer
Main Authors: Ramirez, Servio H., Fan, Shongshan, Zhang, Ming, Papugani, Anil, Reichenbach, Nancy, Dykstra, Holly, Mercer, Aaron J., Tuma, Ronald F., Persidsky, Yuri
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808093/
https://ncbi.nlm.nih.gov/pubmed/20056834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090671
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