Inhibition of Glycogen Synthase Kinase 3β (GSK3β) Decreases Inflammatory Responses in Brain Endothelial Cells

Immune mediators and leukocyte engagement of brain microvascular endothelial cells (BMVECs) contribute to blood–brain barrier impairment during neuroinflammation. Glycogen synthase kinase 3β (GSK3β) was recently identified as a potent regulator of immune responses in in vitro systems and animal mode...

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Detalhes bibliográficos
Main Authors: Ramirez, Servio H., Fan, Shongshan, Zhang, Ming, Papugani, Anil, Reichenbach, Nancy, Dykstra, Holly, Mercer, Aaron J., Tuma, Ronald F., Persidsky, Yuri
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808093/
https://ncbi.nlm.nih.gov/pubmed/20056834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090671
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