Pulmonary Infection with an Interferon-γ-Producing Cryptococcus neoformans Strain Results in Classical Macrophage Activation and Protection

Alternative macrophage activation is associated with exacerbated disease in murine models of pulmonary cryptococcosis. The present study evaluated the efficacy of interferon-γ transgene expression by Cryptococcus neoformans strain H99γ in abrogating alternative macrophage activation in infected mice...

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Autors principals: Hardison, Sarah E., Ravi, Sailatha, Wozniak, Karen L., Young, Mattie L., Olszewski, Michal A., Wormley, Floyd L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808084/
https://ncbi.nlm.nih.gov/pubmed/20056835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090634
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