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Pulmonary Infection with an Interferon-γ-Producing Cryptococcus neoformans Strain Results in Classical Macrophage Activation and Protection

Alternative macrophage activation is associated with exacerbated disease in murine models of pulmonary cryptococcosis. The present study evaluated the efficacy of interferon-γ transgene expression by Cryptococcus neoformans strain H99γ in abrogating alternative macrophage activation in infected mice...

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Detalhes bibliográficos
Main Authors: Hardison, Sarah E., Ravi, Sailatha, Wozniak, Karen L., Young, Mattie L., Olszewski, Michal A., Wormley, Floyd L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808084/
https://ncbi.nlm.nih.gov/pubmed/20056835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090634
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