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Use Of Transgenic Mice In UDP-Glucuronosyltransferase (UGT) Studies

Transgenic mouse models are useful to understand the function and regulation of drug metabolizing enzymes in vivo. This article is intended to describe the general strategies and to discuss specific examples on how to use transgenic, gene knockout, and humanized mice to study the function as well as...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ou, Zhimin, Huang, Min, Zhao, Lizi, Xie, Wen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807998/
https://ncbi.nlm.nih.gov/pubmed/20070245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03602530903208983
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