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Use Of Transgenic Mice In UDP-Glucuronosyltransferase (UGT) Studies

Transgenic mouse models are useful to understand the function and regulation of drug metabolizing enzymes in vivo. This article is intended to describe the general strategies and to discuss specific examples on how to use transgenic, gene knockout, and humanized mice to study the function as well as...

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Main Authors: Ou, Zhimin, Huang, Min, Zhao, Lizi, Xie, Wen
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807998/
https://ncbi.nlm.nih.gov/pubmed/20070245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03602530903208983
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