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Use Of Transgenic Mice In UDP-Glucuronosyltransferase (UGT) Studies

Transgenic mouse models are useful to understand the function and regulation of drug metabolizing enzymes in vivo. This article is intended to describe the general strategies and to discuss specific examples on how to use transgenic, gene knockout, and humanized mice to study the function as well as...

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Bibliografiske detaljer
Main Authors: Ou, Zhimin, Huang, Min, Zhao, Lizi, Xie, Wen
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807998/
https://ncbi.nlm.nih.gov/pubmed/20070245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03602530903208983
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