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Use Of Transgenic Mice In UDP-Glucuronosyltransferase (UGT) Studies

Transgenic mouse models are useful to understand the function and regulation of drug metabolizing enzymes in vivo. This article is intended to describe the general strategies and to discuss specific examples on how to use transgenic, gene knockout, and humanized mice to study the function as well as...

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Bibliografske podrobnosti
Main Authors: Ou, Zhimin, Huang, Min, Zhao, Lizi, Xie, Wen
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807998/
https://ncbi.nlm.nih.gov/pubmed/20070245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03602530903208983
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