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Role of prions in neuroprotection and neurodegeneration: A mechanism involving glutamate receptors?

There is increasing evidence that cellular prion protein plays important roles in neurodegeneration and neuroprotection. One of the possible mechanism by which this may occur is a functional inhibition of ionotropic glutamate receptors, including N-Methyl-D-Aspartate (NMDA) receptors. Here we review...

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Autori principali: Zamponi, Gerald W, Stys, Peter K
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807689/
https://ncbi.nlm.nih.gov/pubmed/19684483
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