Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis

Leucine-rich repeat kinase 2 (LRRK2) functions as a putative protein kinase of ezrin, radixin, and moesin (ERM) family proteins. A Parkinson's disease-related G2019S substitution in the kinase domain of LRRK2 further enhances the phosphorylation of ERM proteins. The phosphorylated ERM (pERM) pr...

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Main Authors: Parisiadou, Loukia, Xie, Chengsong, Cho, Hyun Jin, Lin, Xian, Gu, Xing-Long, Long, Cai-Xia, Lobbestael, Evy, Baekelandt, Veerle, Taymans, Jean-Marc, Sun, Lixin, Cai, Huaibin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807632/
https://ncbi.nlm.nih.gov/pubmed/19890007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3799-09.2009
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