Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation

Medial nucleus tractus solitarius (mNTS) neurons express leptin receptors (LepR) and intramNTS delivery of leptin reduces food intake and body weight. Here, the contribution of endogenous LepR signaling in mNTS neurons to energy balance control was examined. Knockdown of LepR in mNTS and area postre...

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Détails bibliographiques
Auteurs principaux: Hayes, Matthew R., Skibicka, Karolina P., Leichner, Theresa M., Guarnieri, Douglas J., DiLeone, Ralph J., Bence, Kendra K., Grill, Harvey J.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807619/
https://ncbi.nlm.nih.gov/pubmed/20074530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.10.009
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