Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation

Medial nucleus tractus solitarius (mNTS) neurons express leptin receptors (LepR) and intramNTS delivery of leptin reduces food intake and body weight. Here, the contribution of endogenous LepR signaling in mNTS neurons to energy balance control was examined. Knockdown of LepR in mNTS and area postre...

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Bibliografiske detaljer
Main Authors: Hayes, Matthew R., Skibicka, Karolina P., Leichner, Theresa M., Guarnieri, Douglas J., DiLeone, Ralph J., Bence, Kendra K., Grill, Harvey J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807619/
https://ncbi.nlm.nih.gov/pubmed/20074530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.10.009
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