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Spatial mapping of thymic stromal microenvironments reveals unique features influencing T lymphoid differentiation

Interaction of hematopoietic progenitors with the thymic stromal microenvironment induces them to proliferate, adopt the T cell fate, and asymmetrically diverge into multiple T lineages. Progenitors at various developmental stages are stratified among different regions of the thymus, implying that t...

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Bibliografske podrobnosti
Main Authors: Griffith, Ann V, Fallahi, Mohammad, Nakase, Hiroshi, Gosink, Mark, Young, Brandon, Petrie, Howard T
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807413/
https://ncbi.nlm.nih.gov/pubmed/20064453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.09.024
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