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Spatial mapping of thymic stromal microenvironments reveals unique features influencing T lymphoid differentiation
Interaction of hematopoietic progenitors with the thymic stromal microenvironment induces them to proliferate, adopt the T cell fate, and asymmetrically diverge into multiple T lineages. Progenitors at various developmental stages are stratified among different regions of the thymus, implying that t...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807413/ https://ncbi.nlm.nih.gov/pubmed/20064453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.09.024 |
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