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Huntingtin facilitates polycomb repressive complex 2
Huntington's disease (HD) is caused by expansion of the polymorphic polyglutamine segment in the huntingtin protein. Full-length huntingtin is thought to be a predominant HEAT repeat α-solenoid, implying a role as a facilitator of macromolecular complexes. Here we have investigated huntingtin&#...
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| Main Authors: | , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2010
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807366/ https://ncbi.nlm.nih.gov/pubmed/19933700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp524 |
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