Structure of a Eukaryotic Nonribosomal Peptide Synthetase Adenylation Domain That Activates a Large Hydroxamate Amino Acid in Siderophore Biosynthesis

Nonribosomal peptide synthetases (NRPSs) are large, multidomain proteins that are involved in the biosynthesis of an array of secondary metabolites. We report the structure of the third adenylation domain from the siderophore-synthesizing NRPS, SidN, from the endophytic fungus Neotyphodium lolii. Th...

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Detalhes bibliográficos
Main Authors: Lee, T. Verne, Johnson, Linda J., Johnson, Richard D., Koulman, Albert, Lane, Geoffrey A., Lott, J. Shaun, Arcus, Vickery L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807299/
https://ncbi.nlm.nih.gov/pubmed/19923209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.071324
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