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Analysis of Transmembrane Domains 1 and 4 of the Human Angiotensin II AT(1) Receptor by Cysteine-scanning Mutagenesis

The octapeptide hormone angiotensin II (AngII) exerts a wide variety of cardiovascular effects through the activation of the AT(1) receptor, which belongs to the G protein-coupled receptor superfamily. Like other G protein-coupled receptors, the AT(1) receptor possesses seven transmembrane domains t...

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Autores principales: Yan, Liping, Holleran, Brian J., Lavigne, Pierre, Escher, Emanuel, Guillemette, Gaétan, Leduc, Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807285/
https://ncbi.nlm.nih.gov/pubmed/19940150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.077180
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