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Prp43 Bound at Different Sites on the Pre-rRNA Performs Distinct Functions in Ribosome Synthesis

Yeast ribosome synthesis requires 19 different RNA helicases, but none of their pre-rRNA-binding sites were previously known, making their precise functions difficult to determine. Here we identify multiple binding sites for the helicase Prp43 in the 18S and 25S rRNA regions of pre-rRNAs, using UV c...

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Detalhes bibliográficos
Main Authors: Bohnsack, Markus T., Martin, Roman, Granneman, Sander, Ruprecht, Maike, Schleiff, Enrico, Tollervey, David
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806949/
https://ncbi.nlm.nih.gov/pubmed/19941819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.09.039
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