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Identification of protein binding sites on U3 snoRNA and pre-rRNA by UV cross-linking and high-throughput analysis of cDNAs

The U3 small nucleolar ribonucleoprotein (snoRNP) plays an essential role in ribosome biogenesis but, like many RNA–protein complexes, its architecture is poorly understood. To address this problem, binding sites for the snoRNP proteins Nop1, Nop56, Nop58, and Rrp9 were mapped by UV cross-linking an...

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Main Authors: Granneman, Sander, Kudla, Grzegorz, Petfalski, Elisabeth, Tollervey, David
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688437/
https://ncbi.nlm.nih.gov/pubmed/19482942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901997106
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