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Identification of protein binding sites on U3 snoRNA and pre-rRNA by UV cross-linking and high-throughput analysis of cDNAs

The U3 small nucleolar ribonucleoprotein (snoRNP) plays an essential role in ribosome biogenesis but, like many RNA–protein complexes, its architecture is poorly understood. To address this problem, binding sites for the snoRNP proteins Nop1, Nop56, Nop58, and Rrp9 were mapped by UV cross-linking an...

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Auteurs principaux: Granneman, Sander, Kudla, Grzegorz, Petfalski, Elisabeth, Tollervey, David
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688437/
https://ncbi.nlm.nih.gov/pubmed/19482942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901997106
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