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Network of Epistatic Interactions Within a Yeast snoRNA
Epistatic interactions play a fundamental role in molecular evolution, but little is known about the spatial distribution of these interactions within genes. To systematically survey a model landscape of intragenic epistasis, we quantified the fitness of ~60,000 Saccharomyces cerevisiae strains expr...
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| Publicat a: | Science |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137784/ https://ncbi.nlm.nih.gov/pubmed/27080103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf0965 |
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