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Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel

Pre-ribosomal particles evolve in the nucleus through transient interaction with biogenesis factors, before export to the cytoplasm. Here, we report the architecture of the late pre-60S particle purified from Saccharomyces cerevisiae through Arx1, a nuclear export factor with structural homology to...

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Autors principals: Bradatsch, Bettina, Leidig, Christoph, Granneman, Sander, Gnädig, Marén, Tollervey, David, Böttcher, Bettina, Beckmann, Roland, Hurt, Ed
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678077/
https://ncbi.nlm.nih.gov/pubmed/23142978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2438
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