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Tissue Factor and PAR2 Signaling in the Tumor Microenvironment

Diverse oncogenic transformations result in the constitutive expression of tissue factor (TF) in cancer cells. The local and systemic activation of the coagulation cascade has long been a recognized hallmark for aggressive cancer, but genetic mouse models and new experimental therapeutics have only...

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Detalhes bibliográficos
Main Authors: Schaffner, Florence, Ruf, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806842/
https://ncbi.nlm.nih.gov/pubmed/19661489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.177428
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