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Analysis of K-Ras Nuclear Expression in Fibroblasts and Mesangial Cells

BACKGROUND: Ras GTPases are considered cytoplasmic proteins that must be localized to cell membranes for activation, and there are few evidences of the presence of any Ras isoform in nuclei of eukaryotic cells. METHODOLOGY/PRINCIPAL FINDINGS: Using conventional antibodies and inmunocytochemistry, di...

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Autors principals: Fuentes-Calvo, Isabel, Blázquez-Medela, Ana M., Santos, Eugenio, López-Novoa, José M., Martínez-Salgado, Carlos
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806826/
https://ncbi.nlm.nih.gov/pubmed/20090846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008703
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