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Effect of Angiotensin II and Small GTPase Ras Signaling Pathway Inhibition on Early Renal Changes in a Murine Model of Obstructive Nephropathy

Tubulointerstitial fibrosis is a major feature of chronic kidney disease. Unilateral ureteral obstruction (UUO) in rodents leads to the development of renal tubulointerstitial fibrosis consistent with histopathological changes observed in advanced chronic kidney disease in humans. The purpose of thi...

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Detalhes bibliográficos
Main Authors: Rodríguez-Peña, Ana B., Fuentes-Calvo, Isabel, Docherty, Neil G., Arévalo, Miguel, Grande, María T., Eleno, Nélida, Pérez-Barriocanal, Fernando, López-Novoa, José M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101960/
https://ncbi.nlm.nih.gov/pubmed/25101263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/124902
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