Hypertension and Hyperglycemia Synergize to Cause Incipient Renal Tubular Alterations Resulting in Increased NGAL Urinary Excretion in Rats

BACKGROUND: Hypertension and diabetes are the two leading causes of chronic kidney disease (CKD) eventually leading to end stage renal disease (ESRD) and the need of renal replacement therapy. Mortality among CKD and ESRD patients is high, mostly due to cardiovascular events. New early markers of ri...

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Main Authors: Blázquez-Medela, Ana M., García-Sánchez, Omar, Blanco-Gozalo, Víctor, Quiros, Yaremi, Montero, María J., Martínez-Salgado, Carlos, López-Novoa, José M., López-Hernández, Francisco J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141836/
https://ncbi.nlm.nih.gov/pubmed/25148248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105988
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