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Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression

Ebolavirus causes a severe hemorrhagic fever and is divided into five distinct species, of which Reston ebolavirus is uniquely nonpathogenic to humans. Disease caused by ebolavirus is marked by early immunosuppression of innate immune signaling events, involving silencing and sequestration of double...

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Detalhes bibliográficos
Main Authors: Kimberlin, Christopher R., Bornholdt, Zachary A., Li, Sheng, Woods, Virgil L., MacRae, Ian J., Saphire, Erica Ollmann
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806767/
https://ncbi.nlm.nih.gov/pubmed/20018665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910547107
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