Role of the translocation partner in protection against AID-dependent chromosomal translocations

Chromosome translocations between Ig (Ig) and non-Ig genes are frequently associated with B-cell lymphomas in humans and mice. The best characterized of these is c-myc/IgH translocation, which is associated with Burkitt’s lymphoma. These translocations are caused by activation-induced cytidine deami...

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Bibliographic Details
Main Authors: Jankovic, Mila, Robbiani, Davide F., Dorsett, Yair, Eisenreich, Thomas, Xu, Yang, Tarakhovsky, Alexander, Nussenzweig, Andre, Nussenzweig, Michel C.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806756/
https://ncbi.nlm.nih.gov/pubmed/19966290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908946107
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